In-Vivo anti-Microbial activity of Subgingival Salvadora Persica in Chronic Periodontitis

Tahira Hyder; Saima  Quraeshi; Rizma Khan

Authors

Tahira Hyder Ziauddin College of Dentistry
Saima Quraeshi
Rizma Khan

Keywords:

miswak, scaling , root planing, scaling and root planing, Porphyromonas Gingivalis

Abstract

Objective: To evaluate the antimicrobial activity of locally delivered SP gel in nonsurgical therapy of chronic periodontitis (CP).

Material and methods: Sixty-six subjects (n 33/group) with untreated chronic periodontitis were randomized to receive either scaling and root planing (SRP) alone or SRP combined with SP gel. At baseline and 6 weeks the subgingival plaque samples were collected and assessed for the quantity of bacteria Porphyromonas Gingivalis (Pg) using Real Time Polymerase Chain Reaction (RT-PCR).

Results: At 6 weeks, the test group (SRP + SP) had a statistically significant lower Pg count compared to the control group (SRP only) (U=252, p=0.0015).

Conclusion: Local delivery of SP gel into periodontal pockets acted as a beneficial adjunct to SRP and reduced bacteria Pg level in the short follow-up time.

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